Charlotte FC head coach Miguel Angel Ramirez suffered the ax after just 14 games played in the 2022 Major League Soccer (MLS) season on Tuesday.
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Deputy Christian Lattanzio will assume his duties on an interim basis, the organization said through its owner David Tepper.
Three deputies also lost their jobs, including assistant Mikel Antia. The reasons for these dismissals were not specified.
"This is a tough decision, but we believe it's the best for the team at this time," the businessman said in a statement.
“I would like to thank Miguel and his staff for their hard work during our first campaign and wish them the best of luck going forward.”
The expansion club named Ramirez as their head coach on July 7. Charlotte FC sit eighth in the Eastern Conference with five wins and 16 points in 14 games.
In MLS, they lost their last game 2-1 to the Seattle Sounders on Sunday. His next game is scheduled for June 11 against the New York Red Bulls.