- Waters ZetaStar instrument increases the speed and sensitivity of light scattering measurements for biological therapies
News summary:
MILFORD, Mass., Sept. 20, 2023 /PRNewswire/ -- Waters Corporation (NYSE:WAT) introduces the DynaPro™ ZetaStar™ instrument to its Wyatt Technology™ portfolio for nanoparticle analysis. The new instrument simultaneously enables dynamic and static light scattering and dynamic and electrophoretic light scattering (DLS/SLS/ELS) measurements, all in a single device. By combining multiple light scattering techniques and automatically assessing data quality and performing adaptive data capture, the ZetaStar instrument offers higher sensitivity and faster measurements to aid the precise development of complex biologics, using extremely high sample volumes. low.
"The integration of Waters and Wyatt has reached an exciting milestone with the introduction of the ZetaStar instrument as the first new product from our combined companies," said Dr. Udit Batra, president and CEO of Waters Corporation. "The development of effective and safe lipid nanoparticle-based therapies depends on light scattering technologies, such as those integrated into the ZetaStar instrument. It uniquely combines three light scattering measurement techniques in a single device to provide more data points that can provide biologic developers with greater confidence in the drug's efficacy and stability."
A unique flow cell design allows the ZetaStar instrument to be configured with an autosampler, significantly increasing laboratory efficiency and productivity with dozens of unattended measurements that can be run over several hours or even overnight. The instrument's ability to measure DLS and ELS simultaneously along with adaptive data collection functionality improves the speed of traditional ELS measurements by up to 10xi.
The ZetaStar instrument's simple design features a touch-screen interface that allows scientists to collect five critical parameters in a single workflow: size, polydispersity, particle concentration, zeta potential, and turbidity, thus enabling extremely low sample volumes (up to 2 µL). These parameters are essential to characterize the size and charge (zeta potential) of particles and macromolecules in a solution.
The instrument implements a novel algorithm that eliminates possible user errors and biases, facilitating implementation and speeding up results. System uptime has also been improved with features that prevent instrument misalignment, leading to a more efficient laboratory.
Designed to meet the growing needs of biopharmaceutical formulation and development laboratories, the ZetaStar instrument helps scientists working on gene therapy, vaccines, mRNA and proteins develop more stable therapies. It may also benefit materials science R&D laboratories investigating the colloidal stability of new molecules such as quantum dots or other metal nanoparticles used in semiconductor applications.
Additional Resources
About Waters Corporation (www.waters.com) Waters Corporation (NYSE:WAT), a global leader in analytical instruments and software, has pioneered innovations in chromatography, mass spectrometry and thermal analysis serving the life sciences, materials and food for more than 60 years. With approximately 8,000 employees worldwide, Waters operates directly in 35 countries, including 14 manufacturing facilities, and with products available in more than 100 countries.
Waters, Wyatt Technology, DynaPro y ZetaStar son marcas comerciales de Waters Corporation.
Contact:
Janice FoleyDirectora sénior de RR PP, Corporate CommunicationsWaters Corporationjanice_foley@waters.comMóvil: 1.617.823.5555
i Measurements of a known stability standard can take ~80 seconds or more and the same standard is completed in 20 seconds or less (up to 5 times) for the same sample based on internal testing; some ZetaStar beta testers documented up to 10x faster results.
Logo - https://mma.prnewswire.com/media/2077558...
View original content: https://www.prnewswire.com/news-releases/el-instrumento-waters-zetastar-aumenta-la-sensibilidad-de-las-mediciones-de-dispersion-de-luz-301933919.html
